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108
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BMCBI
2007
135views more  BMCBI 2007»
15 years 18 days ago
LIMPIC: a computational method for the separation of protein MALDI-TOF-MS signals from noise
Background: Mass spectrometry protein profiling is a promising tool for biomarker discovery in clinical proteomics. However, the development of a reliable approach for the separat...
Dante Mantini, Francesca Petrucci, Damiana Pierago...
BMCBI
2008
146views more  BMCBI 2008»
15 years 18 days ago
Can molecular dynamics simulations help in discriminating correct from erroneous protein 3D models?
Background: Recent approaches for predicting the three-dimensional (3D) structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potentia...
Jean-François Taly, Antoine Marin, Jean-Fra...
92
Voted
BMCBI
2008
82views more  BMCBI 2008»
15 years 18 days ago
Envelope: interactive software for modeling and fitting complex isotope distributions
Background: An important aspect of proteomic mass spectrometry involves quantifying and interpreting the isotope distributions arising from mixtures of macromolecules with differe...
Michael T. Sykes, James R. Williamson
102
Voted
BMCBI
2008
117views more  BMCBI 2008»
15 years 18 days ago
An iterative block-shifting approach to retention time alignment that preserves the shape and area of gas chromatography-mass sp
Background: Metabolomics, petroleum and biodiesel chemistry, biomarker discovery, and other fields which rely on high-resolution profiling of complex chemical mixtures generate da...
Minho Chae, Robert J. Shmookler Reis, John J. Thad...
105
Voted
CN
2010
160views more  CN 2010»
15 years 17 days ago
ABS: Adaptive buffer sizing for heterogeneous networks
Most existing criteria [3], [5], [8] for sizing router buffers rely on explicit formulation of the relationship between buffer size and characteristics of Internet traffic. However...
Yueping Zhang, Dmitri Loguinov