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RECOMB
2002
Springer
15 years 10 months ago
A new approach to analyzing gene expression time series data
We present algorithms for time-series gene expression analysis that permit the principled estimation of unobserved timepoints, clustering, and dataset alignment. Each expression p...
Ziv Bar-Joseph, Georg Gerber, David K. Gifford, To...
BMCBI
2007
157views more  BMCBI 2007»
14 years 9 months ago
Statistical learning of peptide retention behavior in chromatographic separations: a new kernel-based approach for computational
Background: High-throughput peptide and protein identification technologies have benefited tremendously from strategies based on tandem mass spectrometry (MS/MS) in combination wi...
Nico Pfeifer, Andreas Leinenbach, Christian G. Hub...
67
Voted
BMCBI
2005
107views more  BMCBI 2005»
14 years 9 months ago
Identifying differential expression in multiple SAGE libraries: an overdispersed log-linear model approach
Background: In testing for differential gene expression involving multiple serial analysis of gene expression (SAGE) libraries, it is critical to account for both between and with...
Jun Lu, John K. Tomfohr, Thomas B. Kepler
BMCBI
2011
14 years 1 months ago
Robust joint analysis allowing for model uncertainty in two-stage genetic association studies
Background: The cost efficient two-stage design is often used in genome-wide association studies (GWASs) in searching for genetic loci underlying the susceptibility for complex di...
Dongdong Pan, Qizhai Li, Ningning Jiang, Aiyi Liu,...
102
Voted
NIPS
2001
14 years 11 months ago
Laplacian Eigenmaps and Spectral Techniques for Embedding and Clustering
Drawing on the correspondence between the graph Laplacian, the Laplace-Beltrami operator on a manifold, and the connections to the heat equation, we propose a geometrically motiva...
Mikhail Belkin, Partha Niyogi