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MANSCI
2007
198views more  MANSCI 2007»
15 years 4 months ago
Real Options in Technology Licensing
“Real options” is often viewed as a valuable managerial tool of flexibility and exploration in new technology investment. Real options theory has been criticized, however, due...
Arvids A. Ziedonis
BMCBI
2004
150views more  BMCBI 2004»
15 years 4 months ago
Graph-based iterative Group Analysis enhances microarray interpretation
Background: One of the most time-consuming tasks after performing a gene expression experiment is the biological interpretation of the results by identifying physiologically impor...
Rainer Breitling, Anna Amtmann, Pawel Herzyk
BMCBI
2004
114views more  BMCBI 2004»
15 years 4 months ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....
BMCBI
2004
124views more  BMCBI 2004»
15 years 4 months ago
XHM: A system for detection of potential cross hybridizations in DNA microarrays
Background: Microarrays have emerged as the preferred platform for high throughput gene expression analysis. Cross-hybridization among genes with high sequence similarities can be...
Kristian Flikka, Fekadu Yadetie, Astrid Lægr...
BMCBI
2004
150views more  BMCBI 2004»
15 years 4 months ago
Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs
Background: The wealth of information on protein structure has led to a variety of statistical analyses of the role played by individual amino acid types in the protein fold. In p...
Gareth Williams, Patrick Doherty