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MANSCI
2007
198views more  MANSCI 2007»
14 years 11 months ago
Real Options in Technology Licensing
“Real options” is often viewed as a valuable managerial tool of flexibility and exploration in new technology investment. Real options theory has been criticized, however, due...
Arvids A. Ziedonis
BMCBI
2004
150views more  BMCBI 2004»
14 years 11 months ago
Graph-based iterative Group Analysis enhances microarray interpretation
Background: One of the most time-consuming tasks after performing a gene expression experiment is the biological interpretation of the results by identifying physiologically impor...
Rainer Breitling, Anna Amtmann, Pawel Herzyk
92
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BMCBI
2004
114views more  BMCBI 2004»
14 years 11 months ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....
BMCBI
2004
124views more  BMCBI 2004»
14 years 11 months ago
XHM: A system for detection of potential cross hybridizations in DNA microarrays
Background: Microarrays have emerged as the preferred platform for high throughput gene expression analysis. Cross-hybridization among genes with high sequence similarities can be...
Kristian Flikka, Fekadu Yadetie, Astrid Lægr...
BMCBI
2004
150views more  BMCBI 2004»
14 years 11 months ago
Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs
Background: The wealth of information on protein structure has led to a variety of statistical analyses of the role played by individual amino acid types in the protein fold. In p...
Gareth Williams, Patrick Doherty