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BMCBI
2006
113views more  BMCBI 2006»
15 years 5 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
CORR
2002
Springer
102views Education» more  CORR 2002»
15 years 4 months ago
Quantum Lower Bound for Recursive Fourier Sampling
One of the earliest quantum algorithms was discovered by Bernstein and Vazirani, for a problem called Recursive Fourier Sampling. This paper shows that the Bernstein-Vazirani algo...
Scott Aaronson
141
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BMCBI
2010
80views more  BMCBI 2010»
15 years 4 months ago
Sampling the conformation of protein surface residues for flexible protein docking
Background: The problem of determining the physical conformation of a protein dimer, given the structures of the two interacting proteins in their unbound state, is a difficult on...
Patricia Francis-Lyon, Shengyin Gu, Joel Hass, Nin...
GECCO
2008
Springer
184views Optimization» more  GECCO 2008»
15 years 6 months ago
Analysis of mammography reports using maximum variation sampling
A genetic algorithm (GA) was developed to implement a maximum variation sampling technique to derive a subset of data from a large dataset of unstructured mammography reports. It ...
Robert M. Patton, Barbara G. Beckerman, Thomas E. ...
BMCBI
2010
97views more  BMCBI 2010»
15 years 5 months ago
Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach
Background: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on es...
Dirk Repsilber, Sabine Kern, Anna Telaar, Gerhard ...