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» Scalable Rule-Based Gene Expression Data Classification
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JMLR
2006
103views more  JMLR 2006»
14 years 11 months ago
MinReg: A Scalable Algorithm for Learning Parsimonious Regulatory Networks in Yeast and Mammals
In recent years, there has been a growing interest in applying Bayesian networks and their extensions to reconstruct regulatory networks from gene expression data. Since the gene ...
Dana Pe'er, Amos Tanay, Aviv Regev
RECOMB
2004
Springer
16 years 1 days ago
Predicting Genetic Regulatory Response Using Classification: Yeast Stress Response
We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple orga...
Manuel Middendorf, Anshul Kundaje, Chris Wiggins, ...
BIBM
2008
IEEE
125views Bioinformatics» more  BIBM 2008»
14 years 12 months ago
Systems Biology via Redescription and Ontologies (III): Protein Classification Using Malaria Parasite's Temporal Transcriptomic
This paper addresses the protein classification problem, and explores how its accuracy can be improved by using information from time-course gene expression data. The methods are ...
Antonina Mitrofanova, Samantha Kleinberg, Jane Car...
BMCBI
2004
87views more  BMCBI 2004»
14 years 11 months ago
Selection of informative clusters from hierarchical cluster tree with gene classes
Background: A common clustering method in the analysis of gene expression data has been hierarchical clustering. Usually the analysis involves selection of clusters by cutting the...
Petri Törönen
BMCBI
2010
97views more  BMCBI 2010»
14 years 12 months ago
Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach
Background: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on es...
Dirk Repsilber, Sabine Kern, Anna Telaar, Gerhard ...