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BMCBI
2010
141views more  BMCBI 2010»
14 years 11 months ago
Genome scale prediction of substrate specificity for acyl adenylate superfamily of enzymes based on active site residue profiles
Background: Enzymes belonging to acyl:CoA synthetase (ACS) superfamily activate wide variety of substrates and play major role in increasing the structural and functional diversit...
Pankaj Khurana, Rajesh S. Gokhale, Debasisa Mohant...
SIAMSC
2011
219views more  SIAMSC 2011»
14 years 6 months ago
Fast Algorithms for Bayesian Uncertainty Quantification in Large-Scale Linear Inverse Problems Based on Low-Rank Partial Hessian
We consider the problem of estimating the uncertainty in large-scale linear statistical inverse problems with high-dimensional parameter spaces within the framework of Bayesian inf...
H. P. Flath, Lucas C. Wilcox, Volkan Akcelik, Judi...
WWW
2008
ACM
16 years 9 days ago
Statistical properties of community structure in large social and information networks
A large body of work has been devoted to identifying community structure in networks. A community is often though of as a set of nodes that has more connections between its member...
Jure Leskovec, Kevin J. Lang, Anirban Dasgupta, Mi...
KDD
2008
ACM
172views Data Mining» more  KDD 2008»
16 years 21 hour ago
Structured metric learning for high dimensional problems
The success of popular algorithms such as k-means clustering or nearest neighbor searches depend on the assumption that the underlying distance functions reflect domain-specific n...
Jason V. Davis, Inderjit S. Dhillon
CSB
2005
IEEE
160views Bioinformatics» more  CSB 2005»
15 years 5 months ago
Predicting Continuous Epitopes in Proteins
The ability to predict antigenic sites on proteins is crucial for the production of synthetic peptide vaccines and synthetic peptide probes of antibody structure. Large number of ...
Reeti Tandon, Sudeshna Adak, Brion Sarachan, Willi...