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ALMOB
2007
170views more  ALMOB 2007»
15 years 3 months ago
A spatio-temporal mining approach towards summarizing and analyzing protein folding trajectories
Understanding the protein folding mechanism remains a grand challenge in structural biology. In the past several years, computational theories in molecular dynamics have been empl...
Hui Yang, Srinivasan Parthasarathy, Duygu Ucar
150
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BMCBI
2010
233views more  BMCBI 2010»
15 years 3 months ago
Odefy -- From discrete to continuous models
Background: Phenomenological information about regulatory interactions is frequently available and can be readily converted to Boolean models. Fully quantitative models, on the ot...
Jan Krumsiek, Sebastian Pölsterl, Dominik M. ...
BMCBI
2008
97views more  BMCBI 2008»
15 years 3 months ago
A Population Proportion approach for ranking differentially expressed genes
Background: DNA microarrays are used to investigate differences in gene expression between two or more classes of samples. Most currently used approaches compare mean expression l...
Mugdha Gadgil
134
Voted
BMCBI
2007
123views more  BMCBI 2007»
15 years 3 months ago
PedGenie: meta genetic association testing in mixed family and case-control designs
Background-: PedGenie software, introduced in 2006, includes genetic association testing of cases and controls that may be independent or related (nuclear families or extended ped...
Karen Curtin, Jathine Wong, Kristina Allen-Brady, ...
148
Voted
BMCBI
2008
114views more  BMCBI 2008»
15 years 3 months ago
Dinucleotide controlled null models for comparative RNA gene prediction
Background: Comparative prediction of RNA structures can be used to identify functional noncoding RNAs in genomic screens. It was shown recently by Babak et al. [BMC Bioinformatic...
Tanja Gesell, Stefan Washietl