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CIBCB
2008
IEEE
15 years 9 months ago
Discovering novel cancer therapies: A computational modeling and search approach
— Solid tumors must recruit new blood vessels for growth and maintenance. Discovering drugs that block this tumor-induced development of new blood vessels (angiogenesis) is an im...
Arthur W. Mahoney, Brian G. Smith, Nicholas S. Fla...
JCC
2008
166views more  JCC 2008»
15 years 3 months ago
Reference energy extremal optimization: A stochastic search algorithm applied to computational protein design
: We adapt a combinatorial optimization algorithm, extremal optimization (EO), for the search problem in computational protein design. This algorithm takes advantage of the knowled...
Naigong Zhang, Chen Zeng
ICTAI
2006
IEEE
15 years 9 months ago
Computing Horn Strong Backdoor Sets Thanks to Local Search
In this paper a new approach for computing Strong Backdoor sets of boolean formula in conjunctive normal form (CNF) is proposed. It makes an original use of local search technique...
Lionel Paris, Richard Ostrowski, Pierre Siegel, La...