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BMCBI
2010
119views more  BMCBI 2010»
15 years 3 months ago
Coherent pipeline for biomarker discovery using mass spectrometry and bioinformatics
Background: Robust biomarkers are needed to improve microbial identification and diagnostics. Proteomics methods based on mass spectrometry can be used for the discovery of novel ...
Ali Al-Shahib, Raju Misra, Nadia Ahmod, Min Fang, ...
BMCBI
2008
173views more  BMCBI 2008»
15 years 3 months ago
Improved machine learning method for analysis of gas phase chemistry of peptides
Background: Accurate peptide identification is important to high-throughput proteomics analyses that use mass spectrometry. Search programs compare fragmentation spectra (MS/MS) o...
Allison Gehrke, Shaojun Sun, Lukasz A. Kurgan, Nat...
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BMCBI
2008
156views more  BMCBI 2008»
15 years 3 months ago
ArrayWiki: an enabling technology for sharing public microarray data repositories and meta-analyses
Background: A survey of microarray databases reveals that most of the repository contents and data models are heterogeneous (i.e., data obtained from different chip manufacturers)...
Todd H. Stokes, J. T. Torrance, Henry Li, May D. W...
BMCBI
2008
211views more  BMCBI 2008»
15 years 3 months ago
CUDA compatible GPU cards as efficient hardware accelerators for Smith-Waterman sequence alignment
Background: Searching for similarities in protein and DNA databases has become a routine procedure in Molecular Biology. The Smith-Waterman algorithm has been available for more t...
Svetlin Manavski, Giorgio Valle
BMCBI
2006
145views more  BMCBI 2006»
15 years 3 months ago
Fast-Find: A novel computational approach to analyzing combinatorial motifs
Background: Many vital biological processes, including transcription and splicing, require a combination of short, degenerate sequence patterns, or motifs, adjacent to defined seq...
Micah Hamady, Erin Peden, Rob Knight, Ravinder Sin...