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BMCBI
2008
130views more  BMCBI 2008»
14 years 10 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
BMCBI
2007
91views more  BMCBI 2007»
14 years 10 months ago
A machine learning approach for the identification of odorant binding proteins from sequence-derived properties
Background: Odorant binding proteins (OBPs) are believed to shuttle odorants from the environment to the underlying odorant receptors, for which they could potentially serve as od...
Ganesan Pugalenthi, E. Ke Tang, Ponnuthurai N. Sug...
BMCBI
2008
122views more  BMCBI 2008»
14 years 10 months ago
High-throughput bioinformatics with the Cyrille2 pipeline system
Background: Modern omics research involves the application of high-throughput technologies that generate vast volumes of data. These data need to be pre-processed, analyzed and in...
Mark W. E. J. Fiers, Ate van der Burgt, Erwin Date...
BMCBI
2008
130views more  BMCBI 2008»
14 years 10 months ago
Gene Prospector: An evidence gateway for evaluating potential susceptibility genes and interacting risk factors for human diseas
Background: Millions of single nucleotide polymorphisms have been identified as a result of the human genome project and the rapid advance of high throughput genotyping technology...
Wei Yu, Anja Wulf, Tiebin Liu, Muin J. Khoury, Mar...
BMCBI
2008
136views more  BMCBI 2008»
14 years 10 months ago
GPAT: Retrieval of genomic annotation from large genomic position datasets
Background: Recent genome wide transcription factor binding site or chromatin modification mapping analysis techniques, such as chromatin immunoprecipitation (ChIP) linked to DNA ...
Arnaud Krebs, Mattia Frontini, Làszlò...