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BMCBI
2008
145views more  BMCBI 2008»
14 years 9 months ago
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
Shameek Biswas, John D. Storey, Joshua M. Akey
BMCBI
2008
130views more  BMCBI 2008»
14 years 9 months ago
Gene Prospector: An evidence gateway for evaluating potential susceptibility genes and interacting risk factors for human diseas
Background: Millions of single nucleotide polymorphisms have been identified as a result of the human genome project and the rapid advance of high throughput genotyping technology...
Wei Yu, Anja Wulf, Tiebin Liu, Muin J. Khoury, Mar...
BMCBI
2008
125views more  BMCBI 2008»
14 years 9 months ago
SNPLims: a data management system for genome wide association studies
Background: Recent progresses in genotyping technologies allow the generation high-density genetic maps using hundreds of thousands of genetic markers for each DNA sample. The ava...
Alessandro Orro, Guia Guffanti, Erika Salvi, Fabio...
BMCBI
2008
115views more  BMCBI 2008»
14 years 9 months ago
PARPST: a PARallel algorithm to find peptide sequence tags
Background: Protein identification is one of the most challenging problems in proteomics. Tandem mass spectrometry provides an important tool to handle the protein identification ...
Sara Brunetti, Elena Lodi, Elisa Mori, Maria Stell...
BMCBI
2008
125views more  BMCBI 2008»
14 years 9 months ago
Disambiguation of biomedical text using diverse sources of information
Background: Like text in other domains, biomedical documents contain a range of terms with more than one possible meaning. These ambiguities form a significant obstacle to the aut...
Mark Stevenson, Yikun Guo, Robert J. Gaizauskas, D...