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116
Voted
BMCBI
2010
15 years 2 months ago
2010
Background: In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one ...
106
Voted
BMCBI
2007
15 years 2 months ago
2007
Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
102
Voted
BMCBI
2007
15 years 2 months ago
2007
Background: Array comparative genome hybridization (aCGH) provides information about genomic aberrations. Alterations in the DNA copy number may cause the cell to malfunction, lea...
127
Voted
BMCBI
2008
15 years 2 months ago
2008
Background: The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false po...
112
Voted
BMCBI
2008
15 years 2 months ago
2008
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...