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BMCBI
2008
135views more  BMCBI 2008»
15 years 3 months ago
Inferring the role of transcription factors in regulatory networks
Background: Expression profiles obtained from multiple perturbation experiments are increasingly used to reconstruct transcriptional regulatory networks, from well studied, simple...
Philippe Veber, Carito Guziolowski, Michel Le Borg...
BMCBI
2008
178views more  BMCBI 2008»
15 years 3 months ago
Identification of coherent patterns in gene expression data using an efficient biclustering algorithm and parallel coordinate vi
Background: The DNA microarray technology allows the measurement of expression levels of thousands of genes under tens/hundreds of different conditions. In microarray data, genes ...
Kin-On Cheng, Ngai-Fong Law, Wan-Chi Siu, Alan Wee...
121
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BMCBI
2007
102views more  BMCBI 2007»
15 years 3 months ago
Multivariate Analysis and Visualization of Splicing Correlations in Single-Gene Transcriptomes
Background: RNA metabolism, through 'combinatorial splicing', can generate enormous structural diversity in the proteome. Alternative domains may interact, however, with...
Mark C. Emerick, Giovanni Parmigiani, William S. A...
111
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BMCBI
2008
79views more  BMCBI 2008»
15 years 3 months ago
In silico docking of urokinase plasminogen activator and integrins
Background: Urokinase, its receptor and the integrins are functionally associated and involved in regulation of cell signaling, migration, adhesion and proliferation. No structura...
Bernard Degryse, Juan Fernández-Recio, Vale...
DEBU
2008
100views more  DEBU 2008»
15 years 3 months ago
WAVE: Automatic Verification of Data-Driven Web Services
Data-driven Web services, viewed broadly as interactive systems available on the Web for users and programs, provide the backbone for increasingly complex Web applications. While ...
Alin Deutsch, Victor Vianu