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» Segment-based multiple sequence alignment
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BMCBI
2005
122views more  BMCBI 2005»
14 years 9 months ago
Bayesian coestimation of phylogeny and sequence alignment
Background: Two central problems in computational biology are the determination of the alignment and phylogeny of a set of biological sequences. The traditional approach to this p...
Gerton Lunter, István Miklós, Alexei...
ARC
2007
Springer
123views Hardware» more  ARC 2007»
15 years 1 months ago
Multiple Sequence Alignment Using Reconfigurable Computing
The alignment of multiple protein (or DNA) sequences is a current problem in Bioinformatics. ClustalW is the most popular heuristic algorithm for multiple sequence alignment. Pairw...
Carlos R. Erig Lima, Heitor S. Lopes, Maiko R. Mor...
NAR
1998
86views more  NAR 1998»
14 years 9 months ago
Pfam: multiple sequence alignments and HMM-profiles of protein domains
Pfam contains multiple alignments and hidden Markov model based profiles (HMM-profiles) of complete protein domains. The definition of domain boundaries, family members and alignm...
Erik L. L. Sonnhammer, Sean R. Eddy, Ewan Birney, ...
ISCAPDCS
2007
14 years 11 months ago
PARALLEL-TCOFFEE: A parallel multiple sequence aligner
In this paper we present a parallel implementation of T–Coffee — a widely used multiple sequence alignment package. Our software supports a majority of options provided by the...
Jaroslaw Zola, Xiao Yang, Adrian Rospondek, Sriniv...
BIOINFORMATICS
2005
75views more  BIOINFORMATICS 2005»
14 years 9 months ago
DbW: automatic update of a functional family-specific multiple alignment
: Recent advances in gene sequencing have provided complete sequence information for a number of genomes and as a result the amount of data in the sequence databases is growing at ...
Veronique Prigent, Jean-Claude Thierry, Olivier Po...