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» Segment-based multiple sequence alignment
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BMCBI
2006
92views more  BMCBI 2006»
14 years 9 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
BMCBI
2008
84views more  BMCBI 2008»
14 years 10 months ago
DNAAlignEditor: DNA alignment editor tool
Background: With advances in DNA re-sequencing methods and Next-Generation parallel sequencing approaches, there has been a large increase in genomic efforts to define and analyze...
Hector Sanchez-Villeda, Steven G. Schroeder, Sherr...
RECOMB
2005
Springer
15 years 10 months ago
Using Multiple Alignments to Improve Gene Prediction
The multiple species de novo gene prediction problem can be stated as follows: given an alignment of genomic sequences from two or more organisms, predict the location and structur...
Samuel S. Gross, Michael R. Brent
RECOMB
1997
Springer
15 years 1 months ago
A more efficient approximation scheme for tree alignment
We present a new polynomial time approximation scheme (PTAS) for tree alignment, which is an important variant of multiple sequence alignment. As in the existing PTASs in the liter...
Lusheng Wang, Tao Jiang, Dan Gusfield
ISMB
1998
14 years 11 months ago
Sequence Assembly Validation by Multiple Restriction Digest Fragment Coverage Analysis
DNA sequence analysis depends on the accurate assembly of fragment reads for the determination of a consensus sequence. This report examines the possibility of analyzing multiple,...
Eric C. Rouchka, David J. States