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ICML
2004
IEEE
16 years 18 days ago
A graphical model for protein secondary structure prediction
In this paper, we present a graphical model for protein secondary structure prediction. This model extends segmental semi-Markov models (SSMM) to exploit multiple sequence alignme...
Wei Chu, Zoubin Ghahramani, David L. Wild
BMCBI
2008
187views more  BMCBI 2008»
14 years 12 months ago
PSAT: A web tool to compare genomic neighborhoods of multiple prokaryotic genomes
Background: The conservation of gene order among prokaryotic genomes can provide valuable insight into gene function, protein interactions, or events by which genomes have evolved...
Christine Fong, Laurence Rohmer, Matthew Radey, Mi...
BMCBI
2007
87views more  BMCBI 2007»
14 years 11 months ago
A manually curated database of tetrapod mitochondrially encoded tRNA sequences and secondary structures
Background: Mitochondrial tRNAs have been the subject of study for structural biologists interested in their secondary structure characteristics, evolutionary biologists have rese...
Konstantin Yu Popadin, Leila A. Mamirova, Fyodor A...
BMCBI
2010
94views more  BMCBI 2010»
14 years 12 months ago
A comparative study of conservation and variation scores
Background: Conservation and variation scores are used when evaluating sites in a multiple sequence alignment, in order to identify residues critical for structure or function. A ...
Fredrik Johansson, Hiroyuki Toh
BMCBI
2006
172views more  BMCBI 2006»
14 years 12 months ago
Prediction of cis/trans isomerization in proteins using PSI-BLAST profiles and secondary structure information
Background: The majority of peptide bonds in proteins are found to occur in the trans conformation. However, for proline residues, a considerable fraction of Prolyl peptide bonds ...
Jiangning Song, Kevin Burrage, Zheng Yuan, Thomas ...