Background: The goal of most microarray studies is either the identification of genes that are most differentially expressed or the creation of a good classification rule. The dis...
Background: A primary reason for using two-color microarrays is that the use of two samples labeled with different dyes on the same slide, that bind to probes on the same spot, is...
Ruixiao Lu, Geun-Cheol Lee, Michael Shultz, Chris ...
A great deal of recent research has focused on the challenging task of selecting differentially expressed genes from microarray data (`gene selection'). Numerous gene selecti...
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
The large number of genes and the relatively small number of samples are typical characteristics for microarray data. These characteristics pose challenges for both sample classif...