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SDM
2008
SIAM
157views Data Mining» more  SDM 2008»
14 years 11 months ago
ROC-tree: A Novel Decision Tree Induction Algorithm Based on Receiver Operating Characteristics to Classify Gene Expression Data
Gene expression information from microarray experiments is a primary form of data for biological analysis and can offer insights into disease processes and cellular behaviour. Suc...
M. Maruf Hossain, Md. Rafiul Hassan, James Bailey
BMCBI
2006
86views more  BMCBI 2006»
14 years 9 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao
BMCBI
2008
127views more  BMCBI 2008»
14 years 9 months ago
Gene and pathway identification with Lp penalized Bayesian logistic regression
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...
BMCBI
2004
128views more  BMCBI 2004»
14 years 9 months ago
Comparing transformation methods for DNA microarray data
Background: When DNA microarray data are used for gene clustering, genotype/phenotype correlation studies, or tissue classification the signal intensities are usually transformed ...
Helene H. Thygesen, Aeilko H. Zwinderman
BMCBI
2010
148views more  BMCBI 2010»
14 years 9 months ago
Applying unmixing to gene expression data for tumor phylogeny inference
Background: While in principle a seemingly infinite variety of combinations of mutations could result in tumor development, in practice it appears that most human cancers fall int...
Russell Schwartz, Stanley Shackney