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BMCBI
2007
130views more  BMCBI 2007»
14 years 9 months ago
Reproducibility of microarray data: a further analysis of microarray quality control (MAQC) data
Background: Many researchers are concerned with the comparability and reliability of microarray gene expression data. Recent completion of the MicroArray Quality Control (MAQC) pr...
James J. Chen, Huey-miin Hsueh, Robert R. Delongch...
BMCBI
2010
106views more  BMCBI 2010»
14 years 9 months ago
Selection of optimal reference genes for normalization in quantitative RT-PCR
Background: Normalization in real-time qRT-PCR is necessary to compensate for experimental variation. A popular normalization strategy employs reference gene(s), which may introdu...
Inna Chervoneva, Yanyan Li, Stephanie Schulz, Sean...
BMCBI
2004
117views more  BMCBI 2004»
14 years 9 months ago
Cancer characterization and feature set extraction by discriminative margin clustering
Background: A central challenge in the molecular diagnosis and treatment of cancer is to define a set of molecular features that, taken together, distinguish a given cancer, or ty...
Kamesh Munagala, Robert Tibshirani, Patrick O. Bro...
JIFS
2002
134views more  JIFS 2002»
14 years 9 months ago
Classification of gene expression data using fuzzy logic
Microarray technologies have allowed the measurement of expression of multiple genes simultaneously. Gene expression levels can be used to classify tissues into diagnostic or progn...
Lucila Ohno-Machado, Staal A. Vinterbo, Griffin We...
BMCBI
2005
135views more  BMCBI 2005»
14 years 9 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...