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» Selection of DNA Markers
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ICDM
2006
IEEE
122views Data Mining» more  ICDM 2006»
15 years 5 months ago
Optimal Segmentation Using Tree Models
Sequence data are abundant in application areas such as computational biology, environmental sciences, and telecommunications. Many real-life sequences have a strong segmental str...
Robert Gwadera, Aristides Gionis, Heikki Mannila
BMCBI
2006
114views more  BMCBI 2006»
14 years 11 months ago
A methodology for global validation of microarray experiments
Background: DNA microarrays are popular tools for measuring gene expression of biological samples. This ever increasing popularity is ensuring that a large number of microarray st...
Mathieu Miron, Owen Z. Woody, Alexandre Marcil, Ca...
BMCBI
2002
136views more  BMCBI 2002»
14 years 11 months ago
Making sense of EST sequences by CLOBBing them
Background: Expressed sequence tags (ESTs) are single pass reads from randomly selected cDNA clones. They provide a highly cost-effective method to access and identify expressed g...
John Parkinson, David B. Guiliano, Mark L. Blaxter
BMCBI
2010
155views more  BMCBI 2010»
14 years 11 months ago
FunctSNP: an R package to link SNPs to functional knowledge and dbAutoMaker: a suite of Perl scripts to build SNP databases
Background: Whole genome association studies using highly dense single nucleotide polymorphisms (SNPs) are a set of methods to identify DNA markers associated with variation in a ...
Stephen J. Goodswen, Cedric Gondro, Nathan S. Wats...
BMCBI
2010
89views more  BMCBI 2010»
14 years 11 months ago
Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...
High-Seng Chai, Terry M. Therneau, Kent R. Bailey,...