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BMCBI
2007
101views more  BMCBI 2007»
14 years 9 months ago
Relationship between insertion/deletion (indel) frequency of proteins and essentiality
Background: In a previous study, we demonstrated that some essential proteins from pathogenic organisms contained sizable insertions/deletions (indels) when aligned to human prote...
Simon K. Chan, Michael Hsing, Fereydoun Hormozdiar...
80
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BMCBI
2006
116views more  BMCBI 2006»
14 years 9 months ago
ROKU: a novel method for identification of tissue-specific genes
Background: One of the important goals of microarray research is the identification of genes whose expression is considerably higher or lower in some tissues than in others. We wo...
Koji Kadota, Jiazhen Ye, Yuji Nakai, Tohru Terada,...
BIBE
2005
IEEE
107views Bioinformatics» more  BIBE 2005»
15 years 3 months ago
DSIM: A Distance-Based Indexing Method for Genomic Sequences
In this paper, we propose a Distance-based Sequence Indexing Method (DSIM) for indexing and searching genome databases. Borrowing the idea of video compression, we compress the ge...
Xia Cao, Beng Chin Ooi, HweeHwa Pang, Kian-Lee Tan...
CIBCB
2005
IEEE
15 years 3 months ago
Predicting Single Genes Related to Immune-Relevant Processes
— In this paper we address the problem of predicting gene activities by finding gene regulatory dependencies in experimental DNA microarray data. Only few approaches to infer th...
Christian Spieth, Felix Streichert, Nora Speer, Ch...
CSB
2005
IEEE
125views Bioinformatics» more  CSB 2005»
15 years 3 months ago
On Optimizing Distance-Based Similarity Search for Biological Databases
Similarity search leveraging distance-based index structures is increasingly being used for both multimedia and biological database applications. We consider distance-based indexi...
Rui Mao, Weijia Xu, Smriti R. Ramakrishnan, Glen N...