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BMCBI
2010
89views more  BMCBI 2010»
14 years 11 months ago
Semi-automatic identification of punching areas for tissue microarray building: the tubular breast cancer pilot study
Background: Tissue MicroArray technology aims to perform immunohistochemical staining on hundreds of different tissue samples simultaneously. It allows faster analysis, considerab...
Federica Viti, Ivan Merelli, Mieke Timmermans, Mic...
BMCBI
2007
121views more  BMCBI 2007»
14 years 11 months ago
A constrained polynomial regression procedure for estimating the local False Discovery Rate
Background: In the context of genomic association studies, for which a large number of statistical tests are performed simultaneously, the local False Discovery Rate (lFDR), which...
Cyril Dalmasso, Avner Bar-Hen, Philippe Broët
BMCBI
2008
154views more  BMCBI 2008»
14 years 11 months ago
GenomeMatcher: A graphical user interface for DNA sequence comparison
Background: The number of available genome sequences is increasing, and easy-to-use software that enables efficient comparative analysis is needed. Results: We developed GenomeMat...
Yoshiyuki Ohtsubo, Wakako Ikeda-Ohtsubo, Yuji Naga...
BMCBI
2007
147views more  BMCBI 2007»
14 years 11 months ago
Statistical significance of quantitative PCR
Background: PCR has the potential to detect and precisely quantify specific DNA sequences, but it is not yet often used as a fully quantitative method. A number of data collection...
Yann Karlen, Alan McNair, Sébastien Persegu...
BMCBI
2008
92views more  BMCBI 2008»
14 years 11 months ago
A semiparametric modeling framework for potential biomarker discovery and the development of metabonomic profiles
Background: The discovery of biomarkers is an important step towards the development of criteria for early diagnosis of disease status. Recently electrospray ionization (ESI) and ...
Samiran Ghosh, David F. Grant, Dipak K. Dey, Denni...