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BMCBI
2007
113views more  BMCBI 2007»
14 years 9 months ago
Hinge Atlas: relating protein sequence to sites of structural flexibility
Background: Relating features of protein sequences to structural hinges is important for identifying domain boundaries, understanding structure-function relationships, and designi...
Samuel Flores, Long J. Lu, Julie Yang, Nicholas Ca...
BMCBI
2010
121views more  BMCBI 2010»
14 years 9 months ago
Knowledge-based annotation of small molecule binding sites in proteins
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
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BMCBI
2010
148views more  BMCBI 2010»
14 years 9 months ago
Analysis of interactions between ribosomal proteins and RNA structural motifs
Background: One important goal of structural bioinformatics is to recognize and predict the interactions between protein binding sites and RNA. Recently, a comprehensive analysis ...
Giovanni Ciriello, Claudio Gallina, Concettina Gue...
BMCBI
2010
183views more  BMCBI 2010»
14 years 9 months ago
Active learning for human protein-protein interaction prediction
Background: Biological processes in cells are carried out by means of protein-protein interactions. Determining whether a pair of proteins interacts by wet-lab experiments is reso...
Thahir P. Mohamed, Jaime G. Carbonell, Madhavi Gan...
BMCBI
2007
96views more  BMCBI 2007»
14 years 9 months ago
Structure and function predictions of the Msa protein in Staphylococcus aureus
Background: Staphylococcus aureus is a human pathogen that causes a wide variety of lifethreatening infections using a large number of virulence factors. One of the major global r...
Vijayaraj Nagarajan, Mohamed O. Elasri