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BIOINFORMATICS
2006
142views more  BIOINFORMATICS 2006»
15 years 4 months ago
Intervention in a family of Boolean networks
Motivation: Intervention in a gene regulatory network is used to avoid undesirable states, such as those associated with a disease. Several types of intervention have been studied...
Ashish Choudhary, Aniruddha Datta, Michael L. Bitt...
ICMCS
2006
IEEE
145views Multimedia» more  ICMCS 2006»
15 years 10 months ago
A New Study on Distance Metrics as Similarity Measurement
Distance metric is widely used in similarity estimation. In this paper we find that the most popular Euclidean and Manhattan distance may not be suitable for all data distribution...
Jie Yu, Jaume Amores, Nicu Sebe, Qi Tian
CSB
2002
IEEE
169views Bioinformatics» more  CSB 2002»
15 years 9 months ago
Bayesian Network and Nonparametric Heteroscedastic Regression for Nonlinear Modeling of Genetic Network
We propose a new statistical method for constructing a genetic network from microarray gene expression data by using a Bayesian network. An essential point of Bayesian network con...
Seiya Imoto, SunYong Kim, Takao Goto, Sachiyo Abur...
DEXAW
2007
IEEE
142views Database» more  DEXAW 2007»
15 years 6 months ago
Synopsis Data Structures for XML Databases: Models, Issues, and Research Perspectives
Due to the lack of efficient native XML database management systems, XML data manipulation and query evaluation may be resource-consuming, and represent a bottleneck for several ...
Angela Bonifati, Alfredo Cuzzocrea
WSC
2000
15 years 6 months ago
Analyzing transformation-based simulation metamodels
We present a technique for analyzing a simulation metamodel that has been constructed using a variancestabilizing transformation. To compute a valid confidence interval for the ex...
Maria de los A. Irizarry, Michael E. Kuhl, Emily K...