11394 search results - page 2138 / 2279 » Self-Organizing Data Structures |
172
click to vote
BMCBI
2010
15 years 4 months ago
2010
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
152
click to vote
BMCBI
2010
15 years 4 months ago
2010
Background: An important objective of DNA microarray-based gene expression experimentation is determining interrelationships that exist between differentially expressed genes and ...
133
click to vote
BMCBI
2010
15 years 4 months ago
2010
Background: Automated protein function prediction methods are the only practical approach for assigning functions to genes obtained from model organisms. Many of the previously re...
141
click to vote
BMCBI
2010
15 years 4 months ago
2010
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
113
click to vote
BMCBI
2010
15 years 4 months ago
2010
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...