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139
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GECCO
2008
Springer
175views Optimization» more  GECCO 2008»
15 years 4 months ago
Using differential evolution for symbolic regression and numerical constant creation
One problem that has plagued Genetic Programming (GP) and its derivatives is numerical constant creation. Given a mathematical formula expressed as a tree structure, the leaf node...
Brian M. Cerny, Peter C. Nelson, Chi Zhou
128
Voted
ALMOB
2008
85views more  ALMOB 2008»
15 years 3 months ago
Noisy: Identification of problematic columns in multiple sequence alignments
Motivation: Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data are notoriously plagued by two effects: homoplasies and alignment errors. Larg...
Andreas W. M. Dress, Christoph Flamm, Guido Fritzs...
120
Voted
BMCBI
2010
160views more  BMCBI 2010»
15 years 3 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
174
Voted
BMCBI
2008
200views more  BMCBI 2008»
15 years 3 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
134
Voted
BMCBI
2006
100views more  BMCBI 2006»
15 years 3 months ago
Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
Micah Hamady, M. D. Betterton, Rob Knight