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147
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BMCBI
2008
166views more  BMCBI 2008»
15 years 3 months ago
Biclustering via optimal re-ordering of data matrices in systems biology: rigorous methods and comparative studies
Background: The analysis of large-scale data sets via clustering techniques is utilized in a number of applications. Biclustering in particular has emerged as an important problem...
Peter A. DiMaggio Jr., Scott R. McAllister, Christ...
126
Voted
BMCBI
2008
132views more  BMCBI 2008»
15 years 3 months ago
Very Important Pool (VIP) genes - an application for microarray-based molecular signatures
Background: Advances in DNA microarray technology portend that molecular signatures from which microarray will eventually be used in clinical environments and personalized medicin...
Zhenqiang Su, Huixiao Hong, Hong Fang, Leming M. S...
134
Voted
BMCBI
2006
135views more  BMCBI 2006»
15 years 3 months ago
TF Target Mapper: A BLAST search tool for the identification of Transcription Factor target genes
Background: In the current era of high throughput genomics a major challenge is the genome-wide identification of target genes for specific transcription factors. Chromatin immuno...
Sebastiaan Horsman, Michael J. Moorhouse, Victor C...
131
Voted
BMCBI
2006
137views more  BMCBI 2006»
15 years 3 months ago
Chaos game representation for comparison of whole genomes
Background: Chaos game representation of genome sequences has been used for visual representation of genome sequence patterns as well as alignment-free comparisons of sequences ba...
Jijoy Joseph, Roschen Sasikumar
150
Voted
BMCBI
2006
143views more  BMCBI 2006»
15 years 3 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
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