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» Semantic Mining and Analysis of Gene Expression Data
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BMCBI
2007
168views more  BMCBI 2007»
14 years 10 months ago
GOSim - an R-package for computation of information theoretic GO similarities between terms and gene products
Background: With the increased availability of high throughput data, such as DNA microarray data, researchers are capable of producing large amounts of biological data. During the...
Holger Fröhlich, Nora Speer, Annemarie Poustk...
BMCBI
2007
112views more  BMCBI 2007»
14 years 10 months ago
Selecting dissimilar genes for multi-class classification, an application in cancer subtyping
Background: Gene expression microarray is a powerful technology for genetic profiling diseases and their associated treatments. Such a process involves a key step of biomarker ide...
Zhipeng Cai, Randy Goebel, Mohammad R. Salavatipou...
BIOINFORMATICS
2006
82views more  BIOINFORMATICS 2006»
14 years 10 months ago
ZooDDD: a cross-species database for digital differential display analysis
SUMMARY: In this paper, we combined EST information from the UniGene database and orthologous relationships from the Ensembl database to construct a ZooDDD database. The primary f...
Yun-Ching Chen, Chung-Der Hsiao, Wen-Dar Lin, Chun...
BMCBI
2006
171views more  BMCBI 2006»
14 years 10 months ago
The effect of oligonucleotide microarray data pre-processing on the analysis of patient-cohort studies
Background: Intensity values measured by Affymetrix microarrays have to be both normalized, to be able to compare different microarrays by removing non-biological variation, and s...
Roel G. W. Verhaak, Frank J. T. Staal, Peter J. M....
BMCBI
2007
152views more  BMCBI 2007»
14 years 10 months ago
Difference-based clustering of short time-course microarray data with replicates
Background: There are some limitations associated with conventional clustering methods for short time-course gene expression data. The current algorithms require prior domain know...
Jihoon Kim, Ju Han Kim