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» Semantic Mining and Analysis of Gene Expression Data
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BMCBI
2004
115views more  BMCBI 2004»
14 years 9 months ago
Quantifying the relationship between co-expression, co-regulation and gene function
Background: It is thought that genes with similar patterns of mRNA expression and genes with similar functions are likely to be regulated via the same mechanisms. It has been diff...
Dominic J. Allocco, Isaac S. Kohane, Atul J. Butte
DMKD
2003
ACM
96views Data Mining» more  DMKD 2003»
15 years 3 months ago
Using transposition for pattern discovery from microarray data
We analyze expression matrices to identify a priori interesting sets of genes, e.g., genes that are frequently co-regulated. Such matrices provide expression values for given biol...
François Rioult, Jean-François Bouli...
BMCBI
2011
14 years 4 months ago
A novel approach to the clustering of microarray data via nonparametric density estimation
Background: Cluster analysis is a crucial tool in several biological and medical studies dealing with microarray data. Such studies pose challenging statistical problems due to di...
Riccardo De Bin, Davide Risso
BMCBI
2010
120views more  BMCBI 2010»
14 years 10 months ago
Modeling expression quantitative trait loci in data combining ethnic populations
Background: Combining data from different ethnic populations in a study can increase efficacy of methods designed to identify expression quantitative trait loci (eQTL) compared to...
Ching-Lin Hsiao, Ie-Bin Lian, Ai-Ru Hsieh, Cathy S...
BMCBI
2004
146views more  BMCBI 2004»
14 years 9 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker