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» Sequence Comparison Using a Relational Database Approach
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BMCBI
2010
148views more  BMCBI 2010»
15 years 1 months ago
SKPDB: a structural database of shikimate pathway enzymes
Background: The functional and structural characterisation of enzymes that belong to microbial metabolic pathways is very important for structure-based drug design. The main inter...
Helen A. Arcuri, Geraldo F. D. Zafalon, Evandro A....
VLDB
1987
ACM
92views Database» more  VLDB 1987»
15 years 9 months ago
Mind Your Grammar: a New Approach to Modelling Text
Beginning to create the New Oxford English Dictionary database has resulted in the realization that databases for reference texts are unlike those for conventional enterprises. Wh...
Gaston H. Gonnet, Frank Wm. Tompa
BMCBI
2005
97views more  BMCBI 2005»
15 years 6 months ago
Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data
Background: As genomes evolve after speciation, gene content, coding sequence, gene expression, and splicing all diverge with time from ancestors with close relatives. A minimum e...
Roald Rossnes, Ingvar Eidhammer, David A. Liberles
AAAI
1997
15 years 7 months ago
A Script-Based Approach to Modifying Knowledge Bases
Our goal is to build knowledge acquisition tools that support users in modifying knowledge-based systems. These modi cations may require several individual changes to various comp...
Yolanda Gil, Marcelo Tallis
GCB
1998
Springer
78views Biometrics» more  GCB 1998»
15 years 10 months ago
Computational approaches to identify Leucine Zippers
The leucine zipper is a dimerization domain occurring mostly in regulatory and thus in many oncogenic proteins. The leucine repeat in the sequence has been traditionally used for ...
Erich Bornberg-Bauer