Background: Two problems complicate the study of selection in viral genomes: Firstly, the presence of genes in overlapping reading frames implies that selection in one reading fra...
Saskia de Groot, Thomas Mailund, Gerton Lunter, Jo...
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
Jianwen Fang, Ryan J. Haasl, Yinghua Dong, Gerald ...
Background: Transcription Factors (TFs) and microRNAs (miRNAs) are key players for gene expression regulation in higher eukaryotes. In the last years, a large amount of bioinforma...
Olivier Friard, Angela Re, Daniela Taverna, Michel...
Bioinformaticists use the Basic Local Alignment Search Tool (BLAST) to characterize an unknown sequence by comparing it against a database of known sequences, thus detecting evolu...
Computers have been widely deployed to our daily lives, but human-computer interaction still lacks intuition. Researchers intend to resolve these shortcomings by augmenting tradit...
Matthias Wimmer, Christoph Mayer, Sylvia Pietzsch,...