Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
The shear volume of the results in traditional support based frequent sequential pattern mining methods has led to increasing interest in new intelligent mining methods to find mo...
In contrast to proteins, many classes of functionally related RNA molecules show a rather weak sequence conservation but instead a fairly well conserved secondary structure. Hence ...
We present a solution for the following problem. Given two sequences X = x1x2 · · · xn and Y = y1y2 · · · ym, n ≤ m, find the best scoring alignment of X = Xk [i] vs Y ove...
Background: Many attempts are being made to understand biological subjects at a systems level. A major resource for these approaches are biological databases, storing manifold inf...
Stephan Weise, Ivo Grosse, Christian Klukas, Dirk ...