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» Sequence Comparison Using a Relational Database Approach
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BMCBI
2008
145views more  BMCBI 2008»
15 years 6 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
PAKDD
2007
ACM
115views Data Mining» more  PAKDD 2007»
16 years 11 days ago
Intelligent Sequential Mining Via Alignment: Optimization Techniques for Very Large DB
The shear volume of the results in traditional support based frequent sequential pattern mining methods has led to increasing interest in new intelligent mining methods to find mo...
Hye-Chung Kum, Joong Hyuk Chang, Wei Wang 0010
WABI
2005
Springer
120views Bioinformatics» more  WABI 2005»
15 years 11 months ago
Multiple Structural RNA Alignment with Lagrangian Relaxation
In contrast to proteins, many classes of functionally related RNA molecules show a rather weak sequence conservation but instead a fairly well conserved secondary structure. Hence ...
Markus Bauer, Gunnar W. Klau, Knut Reinert
CPM
2001
Springer
72views Combinatorics» more  CPM 2001»
15 years 10 months ago
Tandem Cyclic Alignment
We present a solution for the following problem. Given two sequences X = x1x2 · · · xn and Y = y1y2 · · · ym, n ≤ m, find the best scoring alignment of X = Xk [i] vs Y ove...
Gary Benson
BMCBI
2006
103views more  BMCBI 2006»
15 years 6 months ago
Meta-All: a system for managing metabolic pathway information
Background: Many attempts are being made to understand biological subjects at a systems level. A major resource for these approaches are biological databases, storing manifold inf...
Stephan Weise, Ivo Grosse, Christian Klukas, Dirk ...