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» Sequence Complexity for Biological Sequence Analysis
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BMCBI
2005
246views more  BMCBI 2005»
14 years 9 months ago
ParPEST: a pipeline for EST data analysis based on parallel computing
Background: Expressed Sequence Tags (ESTs) are short and error-prone DNA sequences generated from the 5' and 3' ends of randomly selected cDNA clones. They provide an im...
Nunzio D'Agostino, Mario Aversano, Maria Luisa Chi...
GECCO
2007
Springer
196views Optimization» more  GECCO 2007»
15 years 4 months ago
An estimation of distribution algorithm with guided mutation for a complex flow shop scheduling problem
An Estimation of Distribution Algorithm (EDA) is proposed to approach the Hybrid Flow Shop with Sequence Dependent Setup Times and Uniform Machines in parallel (HFSSDST-UM) proble...
Abdellah Salhi, José Antonio Vázquez...
BMCBI
2006
130views more  BMCBI 2006»
14 years 10 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
ICCAD
2009
IEEE
147views Hardware» more  ICCAD 2009»
14 years 7 months ago
SAT-based protein design
Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
Noah Ollikainen, Ellen Sentovich, Carlos Coelho, A...
ISMB
1998
14 years 11 months ago
Advanced Query Mechanisms for Biological Databases
Existing query interfaces for biological databases are either based on fixed forms or textual query languages. Users of a fixed form-based query interface are limited to performin...
I-Min A. Chen, Anthony Kosky, Victor M. Markowitz,...