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» Sequence Database Search Using Jumping Alignments
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82
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NAR
1998
86views more  NAR 1998»
14 years 9 months ago
Pfam: multiple sequence alignments and HMM-profiles of protein domains
Pfam contains multiple alignments and hidden Markov model based profiles (HMM-profiles) of complete protein domains. The definition of domain boundaries, family members and alignm...
Erik L. L. Sonnhammer, Sean R. Eddy, Ewan Birney, ...
99
Voted
BMCBI
2007
164views more  BMCBI 2007»
14 years 10 months ago
The Personal Sequence Database: a suite of tools to create and maintain web-accessible sequence databases
Background: Large molecular sequence databases are fundamental resources for modern bioscientists. Whether for project-specific purposes or sharing data with colleagues, it is oft...
Scott A. Givan, Christopher M. Sullivan, James C. ...
CIKM
2009
Springer
15 years 4 months ago
Linear predictive coding representation of correlated mutation for protein sequence alignment
Background: Although both conservation and correlated mutation (CM) are important information reflecting the different sorts of context in multiple sequence alignment, most of ali...
Chan-seok Jeong, Dongsup Kim
BIBE
2006
IEEE
119views Bioinformatics» more  BIBE 2006»
15 years 4 months ago
Large Grain Size Stochastic Optimization Alignment
DNA sequence alignment is a critical step in identifying homology between organisms. The most widely used alignment program, ClustalW, is known to suffer from the local minima pro...
Perry Ridge, Hyrum Carroll, Dan Sneddon, Mark J. C...
BMCBI
2004
119views more  BMCBI 2004»
14 years 10 months ago
PASS2: an automated database of protein alignments organised as structural superfamilies
Background: The functional selection and three-dimensional structural constraints of proteins in nature often relates to the retention of significant sequence similarity between p...
Anirban Bhaduri, Ganesan Pugalenthi, Ramanathan So...