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» Sequence Database Search Using Jumping Alignments
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JCB
2000
105views more  JCB 2000»
14 years 10 months ago
A Greedy Algorithm for Aligning DNA Sequences
For aligning DNA sequences that differ only by sequencing errors, or by equivalent errors from other sources, a greedy algorithm can be much faster than traditional dynamic progra...
Zheng Zhang 0004, Scott Schwartz, Lukas Wagner, We...
90
Voted
IDEAS
1997
IEEE
237views Database» more  IDEAS 1997»
15 years 2 months ago
Sequence Comparison Using a Relational Database Approach
A variety of heterogenous data sources is available in the field of molecular biology. Our focus lies on the biological sequence data, i. e. data maintained in collections like EM...
André Bergholz, Stephan Heymann, Jörg ...
87
Voted
CIBCB
2007
IEEE
15 years 4 months ago
Multiple Sequence Alignment using Fuzzy Logic
—DNA matching is a crucial step in sequence alignment. Since sequence alignment is an approximate matching process there is a need for good approximate algorithms. The process of...
Sara Nasser, Gregory Vert, Monica N. Nicolescu, Al...
BMCBI
2010
104views more  BMCBI 2010»
14 years 10 months ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton
108
Voted
LION
2009
Springer
114views Optimization» more  LION 2009»
15 years 4 months ago
Substitution Matrices and Mutual Information Approaches to Modeling Evolution
Abstract. Substitution matrices are at the heart of Bioinformatics: sequence alignment, database search, phylogenetic inference, protein family classication are based on Blosum, P...
Stephan Kitchovitch, Yuedong Song, Richard C. van ...