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» Sequence alignment for masquerade detection
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NAR
2007
152views more  NAR 2007»
14 years 9 months ago
COMPASS server for remote homology inference
COMPASS is a method for homology detection and local alignment construction based on the comparison of multiple sequence alignments (MSAs). The method derives numerical profiles f...
Ruslan Sadreyev, Ming Tang, Bong-Hyun Kim, Nick V....
BMCBI
2006
92views more  BMCBI 2006»
14 years 9 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
GCB
2000
Springer
137views Biometrics» more  GCB 2000»
15 years 1 months ago
Detecting Sporadic Recombination in DNA Alignments with Hidden Markov Models
Conventional phylogenetic tree estimation methods assume that all sites in a DNA multiple alignment have the same evolutionary history. This assumption is violated in data sets fro...
Dirk Husmeier, Frank Wright
BMCBI
2010
131views more  BMCBI 2010»
14 years 4 months ago
Dynamics based alignment of proteins: an alternative approach to quantify dynamic similarity
Background: The dynamic motions of many proteins are central to their function. It therefore follows that the dynamic requirements of a protein are evolutionary constrained. In or...
Márton Münz, Rune B. Lyngsø, Jo...
HICSS
1994
IEEE
157views Biometrics» more  HICSS 1994»
15 years 1 months ago
A Protein Family Classification Method for Analysis of Large DNA Sequences
A method is described for identification and classification of proteins encoded in large DNA sequences. Previously, an automated system was introduced for the general detection of...
Steven Henikoff, Jorja G. Henikoff