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» Sequence alignment for masquerade detection
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BMCBI
2011
14 years 4 months ago
SNiPlay: a web-based tool for detection, management and analysis of SNPs. Application to grapevine diversity projects
Background: High-throughput re-sequencing, new genotyping technologies and the availability of reference genomes allow the extensive characterization of Single Nucleotide Polymorp...
Alexis Dereeper, Stéphane Nicolas, Loic Le ...
CSB
2003
IEEE
128views Bioinformatics» more  CSB 2003»
15 years 3 months ago
Degenerate Primer Design via Clustering
This paper describes a new strategy for designing degenerate primers for a given multiple alignment of amino acid sequences. Degenerate primers are useful for amplifying homologou...
Xintao Wei, David N. Kuhn, Giri Narasimhan
117
Voted
WABI
2009
Springer
142views Bioinformatics» more  WABI 2009»
15 years 4 months ago
Back-Translation for Discovering Distant Protein Homologies
Background: Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from ...
Marta Gîrdea, Laurent Noé, Gregory Ku...
BMCBI
2006
158views more  BMCBI 2006»
14 years 10 months ago
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...
RECOMB
2006
Springer
15 years 10 months ago
Structural Alignment of Pseudoknotted RNA
In this paper, we address the problem of discovering novel non-coding RNA (ncRNA) using primary sequence, and secondary structure conservation, focusing on ncRNA families with pseu...
Banu Dost, Buhm Han, Shaojie Zhang, Vineet Bafna