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» Sequence alignment for masquerade detection
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CSB
2005
IEEE
129views Bioinformatics» more  CSB 2005»
15 years 3 months ago
ssahaSNP A Polymorphism Detection Tool on a Whole Genome Scale
We present a software package which can detect homozygous SNPs and indels on a eukaryotic genome scale from millions of shotgun reads. Matching seeds of a few kmer words are found...
Zemin Ning, Mario Cáccamo, James C. Mulliki...
BMCBI
2010
145views more  BMCBI 2010»
14 years 10 months ago
JCoDA: a tool for detecting evolutionary selection
Background: The incorporation of annotated sequence information from multiple related species in commonly used databases (Ensembl, Flybase, Saccharomyces Genome Database, Wormbase...
Steven N. Steinway, Ruth Dannenfelser, Christopher...
PSB
2004
14 years 11 months ago
Phylogenetic Motif Detection by Expectation-Maximization on Evolutionary Mixtures
ct The preferential conservation of transcription factor binding sites implies that non-coding sequence data from related species will prove a powerful asset to motif discovery. We...
Alan M. Moses, Derek Y. Chiang, Michael B. Eisen
BMCBI
2010
101views more  BMCBI 2010»
14 years 10 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
ALMOB
2008
81views more  ALMOB 2008»
14 years 10 months ago
Stability of multiple alignments and phylogenetic trees: an analysis of ABC-transporter proteins family
Background: Sequence-based phylogeny reconstruction is a fundamental task in Bioinformatics. Practically all methods for phylogeny reconstruction are based on multiple alignments....
Holger Wagner, Burkhard Morgenstern, Andreas W. M....