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» Shape Distributions and Protein Similarity
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PCM
2010
Springer
179views Multimedia» more  PCM 2010»
14 years 8 months ago
3D Similarity Search Using a Weighted Structural Histogram Representation
A fast and robust 3D retrieval method is proposed based on a novel weighted structural histogram representation. Our method has the following steps: 1) adaptively segment any 3D sh...
Tong Lu, Rongjun Gao, Tuantuan Wang, Yubin Yang
RECOMB
1999
Springer
15 years 1 months ago
Fast detection of common geometric substructure in proteins
We consider the problem of identifying common three-dimensional substructures between proteins. Our method is based on comparing the shape of the α-carbon backbone structures of ...
L. Paul Chew, Daniel P. Huttenlocher, Klara Kedem,...
BMCBI
2008
158views more  BMCBI 2008»
14 years 9 months ago
Metrics for GO based protein semantic similarity: a systematic evaluation
Background: Several semantic similarity measures have been applied to gene products annotated with Gene Ontology terms, providing a basis for their functional comparison. However,...
Catia Pesquita, Daniel Faria, Hugo P. Bastos, Ant&...
COMPLIFE
2006
Springer
15 years 1 months ago
A Point-Matching Based Algorithm for 3D Surface Alignment of Drug-Sized Molecules
Abstract. Molecular shapes play an important role in molecular interactions, e.g., between a protein and a ligand. The `outer' shape of a molecule can be approximated by its s...
Daniel Baum, Hans-Christian Hege
ISBI
2009
IEEE
15 years 4 months ago
Instance-Based Generative Biological Shape Modeling
Biological shape modeling is an essential task that is required for systems biology efforts to simulate complex cell behaviors. Statistical learning methods have been used to buil...
Tao Peng, Wei Wang, Gustavo K. Rohde, Robert F. Mu...