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BMCBI
2007
219views more  BMCBI 2007»
14 years 9 months ago
MetaQTL: a package of new computational methods for the meta-analysis of QTL mapping experiments
Background: Integration of multiple results from Quantitative Trait Loci (QTL) studies is a key point to understand the genetic determinism of complex traits. Up to now many effor...
Jean-Baptiste Veyrieras, Bruno Goffinet, Alain Cha...
BMCBI
2008
135views more  BMCBI 2008»
14 years 9 months ago
Using Generalized Procrustes Analysis (GPA) for normalization of cDNA microarray data
Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
Huiling Xiong, Dapeng Zhang, Christopher J. Martyn...
BMCBI
2008
98views more  BMCBI 2008»
14 years 9 months ago
Assessing probe-specific dye and slide biases in two-color microarray data
Background: A primary reason for using two-color microarrays is that the use of two samples labeled with different dyes on the same slide, that bind to probes on the same spot, is...
Ruixiao Lu, Geun-Cheol Lee, Michael Shultz, Chris ...
CORR
2010
Springer
160views Education» more  CORR 2010»
14 years 9 months ago
Scalable Probabilistic Databases with Factor Graphs and MCMC
Incorporating probabilities into the semantics of incomplete databases has posed many challenges, forcing systems to sacrifice modeling power, scalability, or treatment of relatio...
Michael L. Wick, Andrew McCallum, Gerome Miklau
BMCBI
2006
106views more  BMCBI 2006»
14 years 9 months ago
Methodological study of affine transformations of gene expression data with proposed robust non-parametric multi-dimensional nor
Background: Low-level processing and normalization of microarray data are most important steps in microarray analysis, which have profound impact on downstream analysis. Multiple ...
Henrik Bengtsson, Ola Hössjer