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BMCBI
2010
105views more  BMCBI 2010»
14 years 9 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
BMCBI
2010
202views more  BMCBI 2010»
14 years 9 months ago
NeMo: Network Module identification in Cytoscape
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
Corban G. Rivera, Rachit Vakil, Joel S. Bader
BMCBI
2008
122views more  BMCBI 2008»
14 years 9 months ago
Generating samples for association studies based on HapMap data
Background: With the completion of the HapMap project, a variety of computational algorithms and tools have been proposed for haplotype inference, tag SNP selection and genome-wid...
Jing Li, Yixuan Chen
BMCBI
2007
109views more  BMCBI 2007»
14 years 9 months ago
Seahawk: moving beyond HTML in Web-based bioinformatics analysis
Background: Traditional HTML interfaces for input to and output from Bioinformatics analysis on the Web are highly variable in style, content and data formats. Combining multiple ...
Paul M. K. Gordon, Christoph W. Sensen
BMCBI
2008
141views more  BMCBI 2008»
14 years 9 months ago
EzArray: A web-based highly automated Affymetrix expression array data management and analysis system
Background: Though microarray experiments are very popular in life science research, managing and analyzing microarray data are still challenging tasks for many biologists. Most m...
Yuerong Zhu, Yuelin Zhu, Wei Xu