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» Shotgun Protein Sequencing
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124
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NAR
2011
298views Computer Vision» more  NAR 2011»
14 years 6 months ago
PolyQ: a database describing the sequence and domain context of polyglutamine repeats in proteins
The polyglutamine diseases are caused in part by a gain-of-function mechanism of neuronal toxicity involving protein conformational changes that result in the formation and deposi...
Amy L. Robertson, Mark A. Bate, Steve G. Androulak...
97
Voted
IDEAL
2005
Springer
15 years 5 months ago
Exploiting Sequence Dependencies in the Prediction of Peroxisomal Proteins
Prediction of peroxisomal matrix proteins generally depends on the presence of one of two distinct motifs at the end of the amino acid sequence. PTS1 peroxisomal proteins have a we...
Mark Wakabayashi, John Hawkins, Stefan Maetschke, ...
ANOR
2010
139views more  ANOR 2010»
14 years 10 months ago
Some operations research methods for analyzing protein sequences and structures
Operations Research is probably one of the most successful fields of applied mathematics used in Economics, Physics, Chemistry, almost everywhere onehastoanalyzehugeamountsofdata.L...
Piotr Lukasiak, Jacek Blazewicz, Maciej Milostan
106
Voted
NAR
1998
122views more  NAR 1998»
14 years 11 months ago
The PIR-International Protein Sequence Database
The Protein Information Resource (PIR; http://wwwnbrf.georgetown.edu/pir/ ) supports research on molecular evolution, functional genomics, and computational biology by maintaining...
Winona C. Barker, John S. Garavelli, Daniel H. Haf...
RECOMB
2001
Springer
16 years 2 days ago
A new approach to fragment assembly in DNA sequencing
For the last twenty years fragment assembly in DNA sequencing followed the "overlap - layout - consensus" paradigm that is used in all currently available assembly tools...
Pavel A. Pevzner, Haixu Tang, Michael S. Waterman