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» Shotgun Protein Sequencing
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BMCBI
2010
129views more  BMCBI 2010»
15 years 2 months ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas
BMCBI
2005
60views more  BMCBI 2005»
15 years 1 months ago
PHACCS, an online tool for estimating the structure and diversity of uncultured viral communities using metagenomic information
Background: Phages, viruses that infect prokaryotes, are the most abundant microbes in the world. A major limitation to studying these viruses is the difficulty of cultivating the...
Florent Angly, Beltran Rodriguez-Brito, David Bang...
BMCBI
2008
112views more  BMCBI 2008»
15 years 2 months ago
A simplified approach to disulfide connectivity prediction from protein sequences
Background: Prediction of disulfide bridges from protein sequences is useful for characterizing structural and functional properties of proteins. Several methods based on differen...
Marc Vincent, Andrea Passerini, Matthieu Labb&eacu...
ECCB
2008
IEEE
15 years 8 months ago
Connect the dots: exposing hidden protein family connections from the entire sequence tree
Motivation: Mapping of remote evolutionary links is a classic computational problem of much interest. Relating protein families allows for functional and structural inference on u...
Yaniv Loewenstein, Michal Linial
BMCBI
2007
142views more  BMCBI 2007»
15 years 2 months ago
Predicting and improving the protein sequence alignment quality by support vector regression
Background: For successful protein structure prediction by comparative modeling, in addition to identifying a good template protein with known structure, obtaining an accurate seq...
Minho Lee, Chan-seok Jeong, Dongsup Kim