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CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
15 years 5 months ago
Latent Structure Models for the Analysis of Gene Expression Data
Cluster methods have been successfully applied in gene expression data analysis to address tumor classification. By grouping tissue samples into homogeneous subsets, more systema...
Dong Hua, Dechang Chen, Xiuzhen Cheng, Abdou Youss...
GECCO
2009
Springer
199views Optimization» more  GECCO 2009»
15 years 5 months ago
Using behavioral exploration objectives to solve deceptive problems in neuro-evolution
Encouraging exploration, typically by preserving the diversity within the population, is one of the most common method to improve the behavior of evolutionary algorithms with dece...
Jean-Baptiste Mouret, Stéphane Doncieux
BMCBI
2010
153views more  BMCBI 2010»
15 years 17 days ago
Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...
BMCBI
2007
147views more  BMCBI 2007»
15 years 17 days ago
MaxAlign: maximizing usable data in an alignment
Background: The presence of gaps in an alignment of nucleotide or protein sequences is often an inconvenience for bioinformatical studies. In phylogenetic and other analyses, for ...
Rodrigo Gouveia-Oliveira, Peter Wad Sackett, Ander...
BMCBI
2010
151views more  BMCBI 2010»
15 years 17 days ago
Using diffusion distances for flexible molecular shape comparison
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
Yu-Shen Liu, Qi Li, Guo-Qin Zheng, Karthik Ramani,...