Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Background: The protein structure prediction problem is one of the most challenging problems in biological sciences. Many approaches have been proposed using database information ...
Background: A common clustering method in the analysis of gene expression data has been hierarchical clustering. Usually the analysis involves selection of clusters by cutting the...
To avoid unnecessary maintenance costs in large IT systems resulting from poorly planned changes, it is essential to manage and control changes to the system and to verify that all...