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BMCBI
2010
121views more  BMCBI 2010»
14 years 9 months ago
Knowledge-based annotation of small molecule binding sites in proteins
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
BMCBI
2007
134views more  BMCBI 2007»
14 years 9 months ago
Automatic generation of 3D motifs for classification of protein binding sites
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
Jean-Christophe Nebel, Pawel Herzyk, David R. Gilb...
BMCBI
2007
158views more  BMCBI 2007»
14 years 9 months ago
MetaLook: a 3D visualisation software for marine ecological genomics
Background: Marine ecological genomics can be defined as the application of genomic sciences to understand the structure and function of marine ecosystems. In this field of resear...
Thierry Lombardot, Renzo Kottmann, Gregory Giulian...
BMCBI
2008
130views more  BMCBI 2008»
14 years 9 months ago
A database of phylogenetically atypical genes in archaeal and bacterial genomes, identified using the DarkHorse algorithm
Background: The process of horizontal gene transfer (HGT) is believed to be widespread in Bacteria and Archaea, but little comparative data is available addressing its occurrence ...
Sheila Podell, Terry Gaasterland, Eric E. Allen
BMCBI
2008
125views more  BMCBI 2008»
14 years 9 months ago
Exploration and visualization of gene expression with neuroanatomy in the adult mouse brain
Background: Spatially mapped large scale gene expression databases enable quantitative comparison of data measurements across genes, anatomy, and phenotype. In most ongoing effort...
Christopher Lau, Lydia Ng, Carol Thompson, Sayan D...