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BMCBI
2005
132views more  BMCBI 2005»
14 years 9 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
BMCBI
2005
306views more  BMCBI 2005»
14 years 9 months ago
A method for aligning RNA secondary structures and its application to RNA motif detection
Background: Alignment of RNA secondary structures is important in studying functional RNA motifs. In recent years, much progress has been made in RNA motif finding and structure a...
Jianghui Liu, Jason Tsong-Li Wang, Jun Hu, Bin Tia...
75
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BMCBI
2005
99views more  BMCBI 2005»
14 years 9 months ago
CGH-Profiler: Data mining based on genomic aberration profiles
Background: CGH-Profiler is a program that supports the analysis of genomic aberrations measured by Comparative Genomic Hybridisation (CGH). Comparative genomic hybridisation (CGH...
Falk Schubert, Bernhard Tausch, Stefan Joos, Rolan...
85
Voted
BMCBI
2005
152views more  BMCBI 2005»
14 years 9 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
73
Voted
JSS
2007
115views more  JSS 2007»
14 years 9 months ago
A case study in re-engineering to enforce architectural control flow and data sharing
Without rigorous software development and maintenance, software tends to lose its original architectural structure and become difficult to understand and modify. ArchJava, a recen...
Marwan Abi-Antoun, Jonathan Aldrich, Wesley Coelho