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BMCBI
2006
120views more  BMCBI 2006»
15 years 26 days ago
Optimizing amino acid substitution matrices with a local alignment kernel
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Hiroto Saigo, Jean-Philippe Vert, Tatsuya Akutsu
82
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BMCBI
2006
96views more  BMCBI 2006»
15 years 26 days ago
Structure alignment based on coding of local geometric measures
Background: A structure alignment method based on a local geometric property is presented and its performance is tested in pairwise and multiple structure alignments. In this appr...
Peter L. Chang, Andrew W. Rinne, T. Gregory Dewey
103
Voted
BMCBI
2006
94views more  BMCBI 2006»
15 years 26 days ago
Novel knowledge-based mean force potential at the profile level
Background: The development and testing of functions for the modeling of protein energetics is an important part of current research aimed at understanding protein structure and f...
Qiwen Dong, Xiaolong Wang, Lei Lin
105
Voted
DATAMINE
2006
142views more  DATAMINE 2006»
15 years 25 days ago
Sequential Pattern Mining in Multi-Databases via Multiple Alignment
To efficiently find global patterns from a multi-database, information in each local database must first be mined and summarized at the local level. Then only the summarized infor...
Hye-Chung Kum, Joong Hyuk Chang, Wei Wang 0010
115
Voted
BMCBI
2007
149views more  BMCBI 2007»
15 years 25 days ago
SAMPI: Protein Identification with Mass Spectra Alignments
Background: Mass spectrometry based peptide mass fingerprints (PMFs) offer a fast, efficient, and robust method for protein identification. A protein is digested (usually by tryps...
Hans-Michael Kaltenbach, Andreas Wilke, Sebastian ...