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» Simulating the Hallmarks of Cancer
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92
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BMCBI
2008
97views more  BMCBI 2008»
15 years 16 days ago
A Population Proportion approach for ranking differentially expressed genes
Background: DNA microarrays are used to investigate differences in gene expression between two or more classes of samples. Most currently used approaches compare mean expression l...
Mugdha Gadgil
BMCBI
2010
115views more  BMCBI 2010»
15 years 16 days ago
Assessment and optimisation of normalisation methods for dual-colour antibody microarrays
Background: Recent advances in antibody microarray technology have made it possible to measure the expression of hundreds of proteins simultaneously in a competitive dual-colour a...
Martin Sill, Christoph Schroder, Jörg D. Hohe...
87
Voted
BMCBI
2006
124views more  BMCBI 2006»
15 years 14 days ago
Detection of divergent genes in microbial aCGH experiments
Background: Array-based comparative genome hybridization (aCGH) is a tool for rapid comparison of genomes from different bacterial strains. The purpose of such analysis is to dete...
Lars Snipen, Dirk Repsilber, Ludvig Nyquist, &Arin...
BMCBI
2006
165views more  BMCBI 2006»
15 years 14 days ago
Improved variance estimation of classification performance via reduction of bias caused by small sample size
Background: Supervised learning for classification of cancer employs a set of design examples to learn how to discriminate between tumors. In practice it is crucial to confirm tha...
Ulrika Wickenberg-Bolin, Hanna Göransson, M&a...
84
Voted
VRST
2005
ACM
15 years 6 months ago
AMMP-Vis: a collaborative virtual environment for molecular modeling
Molecular modeling is an important research area, helping scientists develop new drugs against diseases such as AIDS and cancer. Prior studies have demonstrated that immersive vir...
Jeffrey W. Chastine, Jeremy C. Brooks, Ying Zhu, G...