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» Simulations of Simulations in Evolutionary Robotics
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BMCBI
2006
85views more  BMCBI 2006»
14 years 10 months ago
Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shoc
Background: Understanding the relationship between gene expression changes, enzyme activity shifts, and the corresponding physiological adaptive response of organisms to environme...
Ester Vilaprinyó, Rui Alves, Albert Sorriba...
BMCBI
2006
85views more  BMCBI 2006»
14 years 10 months ago
Identification of physicochemical selective pressure on protein encoding nucleotide sequences
Background: Statistical methods for identifying positively selected sites in protein coding regions are one of the most commonly used tools in evolutionary bioinformatics. However...
Wendy S. W. Wong, Raazesh Sainudiin, Rasmus Nielse...
BMCBI
2006
130views more  BMCBI 2006»
14 years 10 months ago
Docking protein domains in contact space
Background: Many biological processes involve the physical interaction between protein domains. Understanding these functional associations requires knowledge of the molecular str...
Stefano Lise, Alice Walker-Taylor, David T. Jones
BMCBI
2006
116views more  BMCBI 2006»
14 years 10 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
COR
2007
134views more  COR 2007»
14 years 10 months ago
Portfolio selection using neural networks
In this paper we apply a heuristic method based on artificial neural networks (NN) in order to trace out the efficient frontier associated to the portfolio selection problem. We...
Alberto Fernández, Sergio Gómez